Chicago Fire3 - 4Portland TimbersPortland Timbers0 - 0Chicago FirePortland Timbers1 - 2Chicago FirePortland Timbers1 - 2Chicago FirePortland Timbers3 - 2Chicago FireChicago Fire2 - 2Portland TimbersPortland Timbers2 - 2Chicago FireChicago Fire1 - 1Portland Timbers
Monterrey2 - 1Chicago Fire
New York Red Bulls1 - 1Chicago Fire
Orlando City SC1 - 2Chicago FireChicago Fire2 - 1Portland Timbers
Cruz Azul1 - 2Chicago Fire
Los Angeles FC1 - 1Portland TimbersPortland Timbers3 - 1
San DiegoChicago Fire2 - 1Portland TimbersPortland Timbers3 - 1
Club Tijuana
Club America3 - 1Portland Timbers| # | Team | P | W | D | L | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|
| 1 |  Vancouver Whitecaps | 20 | 12 | 4 | 4 | +27 | 40 | WLWDD |
| 2 |  Houston Dynamo | 21 | 12 | 2 | 7 | +4 | 38 | LWWWW |
| 3 | Los Angeles FC | 22 | 10 | 5 | 7 | +14 | 35 | DLLDW |
| 4 |  San Jose Earthquakes | 21 | 10 | 3 | 8 | +6 | 33 | LLLLD |
| 5 |  FC Dallas | 21 | 9 | 6 | 6 | +4 | 33 | LWWDL |
| 6 |  St. Louis City | 21 | 9 | 6 | 6 | +3 | 33 | WDWDW |
| 7 |  Colorado Rapids | 21 | 9 | 1 | 11 | +2 | 28 | LWWWL |
| 8 |  Real Salt Lake | 20 | 8 | 4 | 8 | +2 | 28 | LLDDL |
| 9 | Portland TimbersA | 21 | 8 | 4 | 9 | +1 | 28 | DWLWW |
| 10 |  Minnesota United FC | 21 | 7 | 7 | 7 | -2 | 28 | WLDDD |
| 11 | San Diego | 21 | 7 | 6 | 8 | +5 | 27 | WLWDW |
| # | Team | Pts |
|---|---|---|
| 1 | Vancouver Whitecaps | 40 |
| 2 | Houston Dynamo | 38 |
| 3 | Los Angeles FC | 35 |
| 4 | San Jose Earthquakes | 33 |
| 5 | FC Dallas | 33 |
| 6 | St. Louis City | 33 |
| 7 | Colorado Rapids | 28 |
| 8 | Real Salt Lake | 28 |
| 9 | Portland TimbersA | 28 |
| 10 | Minnesota United FC | 28 |
| 11 | San Diego | 27 |
| # | Team | P | W | D | L | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|
| 1 |  Nashville SC | 21 | 15 | 4 | 2 | +26 | 49 | WWWDL |
| 2 |  Inter Miami | 21 | 11 | 6 | 4 | +9 | 39 | LDLDW |
| 3 | Chicago FireH | 20 | 11 | 3 | 6 | +11 | 36 | DWWWL |
| 4 |  New England Revolution | 21 | 10 | 4 | 7 | +7 | 34 | DWLLD |
| 5 |  Charlotte | 21 | 9 | 5 | 7 | +6 | 32 | WDWLW |
| 6 |  FC Cincinnati | 21 | 8 | 7 | 6 | +2 | 31 | DWDWL |
| # | Team | Pts |
|---|---|---|
| 1 | Nashville SC | 49 |
| 2 | Inter Miami | 39 |
| 3 | Chicago FireH | 36 |
| 4 | New England Revolution | 34 |
| 5 | Charlotte | 32 |
| 6 | FC Cincinnati | 31 |
